A medicament that fights colds, as well as all its bothersome symptoms

Grypolek® effectively affects every symptom that accompanies a cold: headache, muscle pain or throat pain, runny nose and cough. Thanks to this, we will quickly feel general relief, which will translate into our better functioning and well-being.


Grypolek®, that is how effectively
fight colds

Manufacturers are outdoing each other in offering more and more new medicines for colds.
A patient who wants to recover quickly often uses the indifferent preparation, but very often it turns out that the improvement occurs only partially. This is because many drugs perform selectively. However, the situation is different in the case of Grypolek®. So what distinguishes it from other competitve products?

Fever and pain

They are the first symptoms that inform us about the situation, that our body has fallen victim to an infection. The paracetamol contained in Grypolek®, quickly restores the correct body temperature and reduces pain that occurs during infection.

Runny nose

Grypolek® effectively reduces swelling of blood vessels, thanks to which we can fully breathe a sigh of relief, with no stuffy or dry nose effect.


Whether it is dry or it is wet, it always interferes with our normal activities.The ingredients of Grypolek® not only soothe its intensity, but also facilitate expectoration.

Grypolek® is a medicine, different from all the others

First of all, Grypolek® has a comprehensive effect on every, not only some, symptoms of a cold:


The finding of fever in the body, indicates not only an increase in body temperature, but also a number of inflammatory processes caused by viral or bacterial infections.


Pain can be defined as the reaction of the nervous system to irritating impulses. They can come from the body, but this is not always the case. In colds, the most common pain is headache and muscle aches.

Dry and wet cough

Coughing is the body's defense mechanism to help clear the airways. A dry (non-productive or barking) cough does not cause the expectoration the mucus. It results from irritation of the bronchial mucosa. It is tiring and troublesome. A wet (productive) cough occurs most often as a consequence of a dry cough. Its characteristic feature is expectoration of the remaining secretions.

Blocked nose and runny nose

A runny nose and stuffy nose are the most common symptoms of a cold. By defending itself against germs, the body produces a secretion that blocks free breathing.

What about a runny nose?

When using Grypolek® the saying: "A treated runny nose and untreated, lasts equally a week"
is not justified. Pseduoephedrine contained in the preparation very quickly reduces nasal congestion, constricting dilated blood vessels. At the same time, it does not leave a feeling
of dryness and destruction of the mucosa, when the runny nose subsides.

How does Grypolek® work?

Thanks to appropriately selected substances, Grypolek®, acting on the above symptoms, fights each of them, at the same time with equal intensity.


Thanks to active substances: dextromethorphans and guaifenesin, Grypolek® effectively fights dry and wet cough. Paracetamol has analgesic and antipyretic effects. Psudoephedrine reduces the swelling and congestion of the nasal mucosa.


Grypolek® has a comprehensive effect on every type of pain that occurs with colds and flu. It supports the fight against cough and runny nose. It works quickly and effectively. It improves airway patency, cleans the sinuses and nose. You will feel better just after the first dose of the medicine.


Medicinal product Grypolek® can be used in flu and cold conditions, by adults and children over the age of 6. Once we use it, we will quickly feel general relief, which will translate into our better functioning.


You can find our preparations in pharmacies
all over the country

Find the pharmacy

Read the leaflet

What is Grypolek® and what is its purpose:

GRYPOLEK®, 24 coated tablets
Paracetamol + Guaifenesin + Pseudoephedrine hydrochloride + Dextromethorphan hydrobromide

Each coated tablet contains: 325 mg of paracetamol, 200 mg of guaifenesin, 30 mg of pseudoephedrine hydrochloride, and 15 mg of dextromethorphan hydrobromide.
Excipients: microcrystalline cellulose, gelatinized starch, sodium carboxymethyl starch, colloidal silica, magnesium stearate, Opadry Yellow Y-5-12821: Hypromellose,Hydroxypropyl cellulose (E 463), Titanium dioxide (E 171), Macrogol, D&C Yellow # 10 Al. Lake, FD&C Yellow # 6 Al. Lake, Carnauba wax (E 903).
Coated tablets.
Oral. The usual dose of GRYPOLEK® is:
Adults and children over 12 years: 2 tablets every 6 to 8 hours, no more than 8 tablets per day, or as prescribed by a doctor.Children 6 to 12 years: 1 tablet every 6 to 8 hours, no more than 4 tablets per day, or as prescribed by a doctor. Adults should not take the medicine for more than 10 days, and children for 5 days. In case of doubt, consult a doctor or pharmacist.
Other special warnings:
Warnings and precautions.
The medicine contains paracetamol.
Grypolek® should not be used simultaneously with other medicines containing paracetamol, sympathomimetics (medicines reducing nasal mucosa congestion, appetite suppressants, or psychostimulants with amphetamine-like effects), and morphine derivatives due to the risk of overdose. Do not exceed the recommended doses. Seek medical advice if cough persists for more than 7 days, or fever for more than 3 days. If nervousness, dizziness, or insomnia occur, discontinue the medicine and consult a doctor. The use of the medicine in patients with liver failure, alcohol abuse, and malnutrition increases the risk of liver damage. Caution should be exercised when using the medicine in individuals with slow metabolism, such as the elderly, due to a higher likelihood of adverse effects associated with dextromethorphan use. The medicine contains azo dyes, which may cause allergic reactions.
Instructions for use:
Action and indications for use:
GRYPOLEK® is a compound medication consisting of four active substances, used in general conditions of cold, headache and muscle pain, fever, sore throat, nasal congestion, and cough caused by cold. Paracetamol exhibits antipyretic and analgesic effects. Pseudoephedrine hydrochloride constricts blood vessels, thereby clearing the nose and sinuses, facilitating unrestricted breathing. Dextromethorphan hydrobromide acts effectively as an antitussive, especially in cases of dry, irritating cough. Guaifenesin is an expectorant that stimulates the bronchial mucosa to produce mucus. It causes thinning and liquefaction of secretions, making them easier to expectorate.
Hypersensitivity to active substances or any excipient. Children under 6 years of age. Hypertension, heart disease, diabetes, hyperthyroidism, difficulty urinating associated with prostate disease, severe kidney and liver failure, anemia. Concurrent use with other medicines containing paracetamol. Use of Parkinson's disease medications, antidepressants, monoamine oxidase inhibitors, and within two weeks after discontinuation of monoamine oxidase inhibitors.
Interactions with other drugs and other types of interactions:
Drugs that accelerate gastric emptying, e.g., metoclopramide, accelerate the absorption of paracetamol, while drugs that delay its emptying, e.g., propantheline, as well as cholestyramine and all anticholinergics, may delay its absorption. Paracetamol used together with rifampicin, antiepileptic drugs, barbiturates increases the risk of liver damage, whereas with zidovudine, it may intensify the toxic effects of this substance on the bone marrow. Paracetamol prolongs the half-life of chloramphenicol and increases its toxicity, it may also intensify the action of anticoagulant drugs (coumarins). Observations of interactions between sympathomimetics (ephedrine, noradrenaline) and centrally acting antihypertensive drugs (guanethidine, methyldopa) indicate that the use of pseudoephedrine may increase blood pressure and cause heart rhythm disturbances. Drugs inhibiting the functioning of cytochrome CYP2D6, e.g., fluoxetine, haloperidol, quinidine, venlafaxine, may inhibit the metabolism of dextromethorphan. Concurrent use of drugs containing pseudoephedrine and certain dietary supplements containing ephedrine derivatives increases the risk of adverse effects. Due to the high probability of interactions, do not use with monoamine oxidase inhibitors (MAO) or within two weeks after discontinuation of treatment, as well as with serotonin reuptake inhibitors.
Pregnancy and breastfeeding:

GRYPOLEK® should not be used in pregnant women or during breastfeeding.
Driving and operating machinery:
During the use of GRYPOLEK® caution should be exercised while driving and operating machinery, due to the possibility of adverse effects on the central nervous system, e.g., drowsiness, hallucinations.
Adverse reactions:

Like any medicine, this medicine may cause adverse reactions, although not everyone experiences them. The active substances contained in GRYPOLEK® rarely cause the following adverse reactions: nausea, vomiting, heartburn, liver dysfunction, heart rhythm disturbances, changes in blood pressure, and changes in blood morphology, including: anemia (a set of symptoms caused by iron deficiency), methemoglobinemia (a condition in which hemoglobin contains trivalent instead of divalent iron ions, losing the ability to transport oxygen), agranulocytosis (a disease caused by a significant decrease in the number of granulocytes, one of the types of white blood cells), dizziness, visual, sensory, and taste disturbances, drowsiness, anxiety, nervousness, hallucinations, psychomotor agitation. The medicine may cause asthma attacks and skin changes. Other adverse reactions include renal dysfunction, urinary tract stones (a disease associated with the formation of stones in the kidneys), and urinary retention. If any adverse reactions occur, including any possible adverse reactions not listed above, consult a doctor or pharmacist.
Do not exceed the recommended doses, due to the high probability of adverse effects, which may manifest as gastrointestinal disorders: nausea, vomiting, abdominal pain, jaundice, diarrhea, and neurological disorders: psychiatric disturbances, drowsiness, as well as cardiovascular disorders, including heart rhythm disturbances, increased blood pressure. In case of the above symptoms, contact a doctor immediately. Do not use this medicine after the expiration date stated on the box.
Storage conditions:
Store in a dry place, in a closed container.
Keep the medicine out of reach and sight of children.
Marketing Authorization Holder and Manufacturer:
KATO Labs Sp. z o.o.,
ul. Marszałkowska 138/82,
00-004 Warsaw.

Marketing Authorization Number:
4394, issued by the President of the Office for Registration of Medicinal Products, Medical Devices, and Biocidal Products.

Information on availability category:
Over-the-counter medicine.